中国药科大学始建于1936年，是教育部直属“211工程”和国家“双一流”建设高校，是我国历史悠久、享有盛誉的药学人才孵化基地。有机化学是药学及相关专业的重要基础课，也是连接化学和生物学两大学科的桥梁。从某种意义上说，学好这门课就拥有了进入药学殿堂的敲门砖。

      本课主要包括绪论、烷烃和环烷烃、立体化学基础、烯烃、炔烃和二烯烃、芳烃、卤烃、醇酚醚、醛酮、羧酸和取代羧酸、羧酸衍生物、碳负离子的反应、有机含氮化合物、杂环化合物、糖类、萜类和甾体等16个章节。根据药学及相关专业的特点，教学内容各有侧重。另外还加入了立体化学、同分异构/芳香性、取代基效应/有机反应的选择性、有机化合物命名、结构推断、反应机理、有机合成（上）、有机合成（下）等8个精讲专题。其中的“有机化合物命名”依据中国化学会《有机化合物命名原则2017》进行了专题总结，对新命名法的学习很有帮助。在学习有机化学的基础知识后，初学者常在分析实际问题时遇到困难。为此，课程还把习题课视频呈现给大家，帮助学习者逐步掌握有机化学的思维方式。

      课程在讲解基础知识的同时，着力营造自主学习的环境，在整个开课周期提供较高质量的答疑和个性化辅导。学生还能参与富有启发性的“药味十足”的讨论，体验分析问题、解决问题的思维训练，同时强化沟通表达能力。课程还设有名师名家访谈栏目，将学界和企业界人士的真知灼见与你分享。准备好挥洒汗水吧！课程团队祝你“学的好、有见识、会思考”。

    China Pharmaceutical University (CPU) was founded in 1936, which is one of the “211 project” key universities affiliated to the Ministry of Education of China and a national "double first-class" construction university. It is a pharmaceutical talent incubation base with a long history and high reputation in China. Organic chemistry is not only an important basic course of pharmacy and related majors, but also a bridge connecting chemistry and biology. In a sense, to learn this course well is to have the key to the palace of pharmacy.

    This course mainly includes sixteen chapters: introduction, alkanes / cycloalkanes, elementary stereochemistry, alkenes, alkynes / dienes, aromatic hydrocarbons, halocarbons, alkenols / phenols / ethers, aldehydes and ketones, carboxylic acids and substituted carboxylic acids, carboxylic acid derivatives, reactions of carbanion, organic nitrogen compounds, heterocyclic compounds, sugars, terpenes and steroids. According to the characteristics of pharmacy and related majors, the teaching contents have different emphases.  In these chapters, eight intensive topics are added: stereochemistry, isomerism / aromaticity, substituent effect / selectivity of organic reactions, nomenclature of organic compounds, structure inference, reaction mechanism, organic synthesis (I) and organic synthesis (II). The "nomenclature of organic compounds" is a special summary based on the "Principles for Nomenclature of Organic Compounds 2017" published by the Chinese Chemical Society, which is very helpful for the study of the new principles of nomenclature. After learning the basic knowledge of organic chemistry, beginners often encounter difficulties in analyzing practical problems. Therefore, the course presents the video of the exercise class to help learners gradually master the thinking mode of organic chemistry.

    While explaining the basic knowledge, the course focuses on creating an autonomous learning environment, and provides high-quality Q & A and personalized guidance throughout the course cycle. Students can also participate in the enlightening "medicinal flavor" discussion, experience the thinking training of analyzing and solving problems, and strengthen the ability of communication and expression. There is an interview column for famous teachers and experts, the insights of scholars and business people will be shared with you. Get ready to sweat! The course team wishes you would learning well, be clear-sighted and thoughtful.

1. 课程的目的和任务

       有机化学是化学的一个重要分支，着重研究有机化合物的结构、性质与反应。有机化学也是高等药学教育的一门重要基础课。本课程通过视频讲授、在线答疑、习题等各个教学环节，使学生比较牢固地掌握有机化学的一些基本知识，基本理论和基本反应，对一些重要的有机反应机理有较好的理解，对有机化学发展的现状及其与药学的关系有所了解。

2. 课程的基本内容和要求

    (1) 掌握各类化合物的命名、物理性质和制备方法。

    (2) 掌握各类化合物的结构、典型反应和反应性。

    (3) 掌握几类典型反应机理和各种异构现象。

    (4) 熟悉几类重要反应中的立体化学和取代基效应。

    (5) 对于开拓知识面的内容作一般性的了解。

3. 学分：5

4. 学时：85

5. 性质：必修课 

1. General aims

    Organic chemistry is an important branch of chemistry, focusing on the structure, properties and reactions of organic compounds. Organic chemistry is also an important basic course in higher pharmaceutical education. This course enables students to grasp some basic knowledge, theories and reactions of organic chemistry, have a better understanding of some important mechanism of organic reaction, and understand the development status of organic chemistry and its relationship with pharmacy through various teaching links such as video teaching, online Q & A and exercise.

2. Contents and learning outcomes

    (1) Master naming, physical properties and synthesis of various types of organic compounds.

    (2) Master structures, typical reactions of various types of organic compounds.

    (3) Master some classic and important organic reaction mechanisms.

    (4) Know the stereo chemistry of some typical reactions.

    (5) Understand some advance topics of organic chemistry.

3. Credits: 5

4. Class hours: 85

5. Character：Compulsory class

基础化学、无机化学。

1. 陆涛主编，《有机化学》，第9版，人民卫生出版社，2022年；

2. 王积涛主编，《有机化学》，第3版，南开大学出版社，2009年；

3. 胡宏纹主编，《有机化学》上下册，第4版，高等教育出版社，2013年；

4. 陆涛主编，《有机化学学习指导与习题集》，第5版，人民卫生出版社，2023年；

5. 芦金荣主编，《有机化学复习指南与习题精选》，第2版，化学工业出版社，2020年；

6. 汪波、彭爱云、黄志纾主编，《基础有机化学》，高等教育出版社，2019年；

7. 李小瑞主编，《有机化学》，第2版，化学工业出版社，2018年；

8. [美] K.彼得·C. 福尔哈特，尼尔·E.肖尔著，戴立信等译，《有机化学结构与功能》，原著第8版，化学工业出版社，2020年.

Q :  还有哪些在线课程资源值得推荐？

A :   （1）清华大学李艳梅有机化学（https://list.youku.com/albumlist/show/id_16099033.html）

（2）耶鲁大学公开课：新生有机化学（共37集，https://open.163.com/special/sp/freshmanorganicchemistry.html）

（3）耶鲁大学公开课：新生有机化学II（共38集，https://open.163.com/special/opencourse/youjihuaxue2.html）

Q :  在哪里能看到《有机化学命名原则2017》这本书？

A :  这本书由科学出版社于2018年1月出版，纸质书籍可以在图书零售机构购买，另外中国化学会官网还提供在线阅读的渠道（https://www.chemsoc.org.cn/library/copy/24.html）

Q :  通过什么途径来了解IUPAC的有机化合物命名体系？

A :  可以阅读IUPAC官网内的Nomenclature of Organic Chemistry <Blue book>（https://iupac.org/what-we-do/books/bluebook/）

Q :  如何方便地查找化合物的IUPAC名？

A :  （1）可登录PubChem数据库（https://pubchem.ncbi.nlm.nih.gov/），检索到该化合物后在“Names and Identifiers”项下即可查看到IUPAC名。

（2）Marvin：免费。在线工具Marvin JS可以标记手性碳构型（https://marvinjs-demo.chemaxon.com/latest/index.html）；离线软件可给出IUPAC命名，下载链接 https://cactus.nci.nih.gov/chemical/structure

（3）ChemDoodle：绘图软件，可给出IUPAC命名（https://www.chemdoodle.com/）

Q :  有什么学习立体化学的工具可以推荐？

A :  molview：免费在线工具，可绘制分子结构并生成其优势构象，并在3D视窗内多角度浏览，适合学习立体化学（https://molview.org/）