Coverage includes in-depth study of: (i) the structure of organic compounds and the functional groups (bonding, acid-base properties, nomenclature, conformations, stereochemistry), and (ii) the synthesis and reactivity (including detailed mechanisms) of alkanes, alkenes, alkynes, halides, alcohols, ethers, epoxides, sulfides and biomolecules (lipids, carbohydrates, proteins, and nucleic acids). Laboratory experiments are related to topics covered in lectures and emphasize organic laboratory techniques, synthesis and spectroscopic characterization of organic molecules.
In lecture, students are given:
Lecture quizzes, and homework assignments - 10% of final grade
A two-hour comprehensive final exam - 80% of final grade
In laboratory, students will be evaluated based on their performance on:
Lab reports, and/or assessments of lab practice - 10% of final grade
Chapter1 Introduction
Section2
Section1
Chapter2 Alkanes
Section1
Section2
Homework1
Chapter3 Cycloalkanes
Pre-class video for chair conformation
Homework2
Chapter4 Stereochemistry
!! EXPERIMENT Polarimeter
Pre-class video for R/S configuration
Pre-class video for chirality
Homework3
Chapter5 Alkenes
After-class video for addition polymerization
Pre-class video for electrophilic addition reaction
!! EXPERIMENT Steam distillation - Limonene from Lemon
Homework4
Chapter6 Alkynes
After-class video for silver acetylide
Combustion of acetylene
Homework5
Chapter7 Alkyl halides
Pre-class video for SN1 & SN2 reactions
Homework6
Chapter8 Aromatic compounds
Pre-class video for ortho- meta- para- position
Story of benzene ring
Homework7
Chapter9 Alcohols and phenols
Pre-class video for alcohol
Homework8
Chapter10 Ethers and epoxides
Pre-class video for diethyl ether
Homework9
Chapter11 Aldehydes and ketones
After class video for phenol-formaldehyde resin
After class video for aldol condensation
Homework10
Chapter12 Carboxylic Acids
Purification of Benzoic Acid by Crystallization
Pre-class video for carboxylic acids
Homework11
Chapter13 Carboxylic Acid Derivatives
!! EXPERIMENT Preparation of ethyl acetate
!! EXPERIMENT Preparation of aspirin
Pre-class video for esters
Homework12
Chapter14 Amines and Heterocycles
After-class video for aniline
Homework13
Aspirin to Tylenol
Part 1 Extracting Aspirin from Pills
Part 6 Acetaminophen from p-aminophenol
Part 2 Conversion of ASA to Salicylic Acid
Part 4 Mono-nitration of Phenol
Part 5 Reducing p-nitrophenol to p-aminophenol
Part 3 Phenol from Salicylic Acid
Chapter15 Carbohydrates
Extracting Starch from Potatoes
Chapter16 Amino Acids, Peptides, and Proteins
Solid Phase Peptide Synthesis
Chapter17 Lipids
Turning soap into oil
Chapter18 Nucleic acids
What is DNA and what does it taste like?
综合复习