Synthetic Biology
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spContent=In 1993, in his movie "Jurassic Park", Steven described scientists developed dinosaur embryos to create prehistoric behemoth, using dinosaur blood inside mosquito preserved in natural amber, as well as DNA molecules from fossils. This is the "movie version" of Synthetic Biology.
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课程概述

        Synthetic Biology is a new interdisciplinary subject, including Biology, Engineering, Mathematics, Computer Science, Physics and Chemistry. The involved scientific knowledge and technology are the frontiers of modern scientific development. Through the study of this course, students can extensively explore the intersection and integration of different subjects, broaden their knowledge, improve their comprehensive quality, and enhance their innovative spirit, innovative consciousness and entrepreneurial ability.

       Synthetic Biology is to engineer the synthesis of biological systems and the connection of genetic circuits. Like the manufacturing method of integrated circuits, design, construction and redesign are the general flow. The ultimate goal of Synthetic Biology is to achieve the biological functions needed by people through the process of rational design and redesign, and to realize it through experiments, so as to promote the research on disease diagnosis, drug treatment, gene coding, and the origin of life. Its main contents include the principle of modularization and standardization of biological gene parts, assembly and characterization of gene parts, classic artificial gene circuits in Synthetic Biology, genome synthesis and editing technology, etc.

授课目标

Knowledge objectives:

    1. Master the principles of modularization and standardization of biological parts, assembly and characterization of biological parts, classic artificial gene circuits in synthetic biology, and some DNA assembly techniques.

    2. Familiar with the safety control and ethics of artificial life system, and strictly abide by them in practice.

    3. Understand the applications of Synthetic Biology in industry, agriculture, energy and medical health fields.

    4. Learn the excellent projects of international genetic engineering machine competition (iGEM) to broaden academic horizon.

Ability objectives:

    To develop students' ability to analyze and solve problems comprehensively using multidisciplinary knowledge; to enhance students' innovative spirit, innovative consciousness, and entrepreneurial ability in solving problems.

Quality objectives:

    To cultivate students' good biosafety control consciousness and control ability, and to have noble professional ethics and ethical standards.


课程大纲
预备知识

Molecular Biology, Systems Biology, Advanced Mathematics

参考资料

1.Introduction to Synthetic Biology, Kai Song, Beijing: Science Press, 2010.

2.Introduction to Synthetic Biology》, Chun Li, Beijing: Chemical Industry Press, 2019.

3.Synthetic Biology, A Primer, Revised Edition, Baldwin, Bayer, et al. Imperial College Press, 2015.

4.BioBuilder: Synthetic Biology in the Lab, Natalie Kuldell, et al. O'Reilly, 2015.

5.Synthetic Biology, Springer Protocol, Karen M. Polizzi, Cleo Kontoravdi, Humana Press, 2013.

6.A Introduction to Systems Biology》,Uri AlonYifei Wang translatio. Chemical Industry Press, 2009.

7. iGEM websitehttps://igem.org/Main_Page


常见问题

Declaration:

1. Some pictures, animations and videos in this course which are used for teaching purposes come from the Internet. If they violate your rights and interests, please contact us.

2. Please respect teachers and classmates, and be kind to others.

3. Please do not release illegal or prohibited information on the platform.


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