spContent=The course of analytical chemistry provided by the teaching team of Dalian University of Technology, which has been one member of the national bilingual demonstration team since 2008. The team has richful experience and course resources, which can help you to grasp the principles and application of many analytical methods. Analytical chemistry provide you methodes to recognize and estimate the chemical compositions and properties of materials, that is, analytical chemistry is very close to our lives and societies.
The course of analytical chemistry provided by the teaching team of Dalian University of Technology, which has been one member of the national bilingual demonstration team since 2008. The team has richful experience and course resources, which can help you to grasp the principles and application of many analytical methods. Analytical chemistry provide you methodes to recognize and estimate the chemical compositions and properties of materials, that is, analytical chemistry is very close to our lives and societies.
—— 课程团队
课程概述
Analytical chemistry is a measurement science consisting of a set of powerful ideas and methods that are useful in all fields of science and medicine. The analytical chemistry course of Dalian University of Technology is designed primarily for the students majored in Chemical Engineering,Biology,Polymer Science,and so on. The course is composed of eight sections, including introduction, titrimetric method, electrochemical method, chromatograph method, atomic absorption spectroscopy, and molecular absorption spectrometry of UV-vis absorption, IR, and 1HNMR. It covers the methods of quantitative analysis, qualitative analysis, and structural analysis. To help the students to well understand the principle and instrumental structure of those analytical methods, a series of advanced digital resources, such as 3D cartoon and virtual simulation experiments, are provided in this course. The teaching course team is composed of six professors with good analytical chemistry background. Benefited from the experienced teaching team and advanced learning materials, this team has been awarded as the National Excellent Course, the National Excellent Resource Sharing Course, and the National Excellent MOOC. Wish to join hands with you to appreciate the charm of analytical chemistry!
授课目标
After learning this course, you need
(1) Be able to explain the principles and to distinguish the application scope and instrument composition of different analytical methods;
(2) Be able to select the appropriate analytical chemistry method, design the experimental scheme, correctly express the analytical results, and evaluate the reliability of the analytical results according to the properties of the analytical samples.
(3) Be able to analyze the structure and composition of organic compounds and explain the analytical process.
课程大纲
Introduction
课时目标：1． To know the property and application of analytical chemistry, the task and demands of the curriculum.2． To grasp the classification of AC methods and the fundamental characteristics of different methods.3． To keep abreast of the general steps of analytical process.4． To know the history, development tendency and forward fields of analytical chemistry.
1.1 The Nature, Scope, and Function of Analytical Chemistry
1.2 Classification of Analytical Methods
1.3 History and Trends in Analytical Methods
1.4 Sampling, Standardization, and Calibration
The Assessment of Analytical Data (Section 2.1~2.4)
课时目标：1． To master: the expression of error; the characteristics，elimination and detection methods of systematic error and random error; the method and way to improve the accuracy.2． To master the definitions, application and relationship of precision and accuracy; To grasp the definition and function of confidence level and confidence interval; to be able to calculate confidence interval with the mean.
2.1 Defination of Accuracy and Error
2.2 Defination of Precision and Deviation
2.3 Relationship between Accuracy and Precision
2.4 Nature and Origin of Errors
The Assessment of Analytical Data (Section 2.5~2.11)
课时目标：1． To grasp the way to reject the questionable data and evaluate the quantitative analytical data; to know the concept, computation rules and rounding of significant figures; to master the expression way of the determinating results, statistical rule of error distribution, the evaluation of reliability on analytical methods.2． To know the delivery of error, regression analytical method of calibration curve.
2.5 Statistical Data Treatment
2.6 Confidence Level and Confidence Intervals
2.7 Evaluation of Quantitative Analytical Data
2.8 Error Transmission
2.9 Selection of Analytical Methods and the Accuracy Improvement
2.10 Significant Figures
2.11 Counting Rules of Significant Figures
Titrimetric analysis (Section 3.1~3.3)
课时目标：1．To master: characteristic and classification of titrimetry methods, requirements of titrimetric analysis for chemical reactions; preparation methods of standard solution, determination and expression way of concentration, the concepts of primary standard and the demands for primary standards while preparing standard solution directly, difference between the stoicheometric point and the end point, the four kinds of titration and their relevant calculation, the definition of titer and its calculation.
3.1 Overview of Titration Analysis
3.2 Acid Base Equilibria and Weak Acid Distribution Curve
3.3 Other Equilibria and pH of Solution
Titrimetric analysis (Section 3.4~3.9)
课时目标：1．To grasp the fundamental principles of chemical equilibrium, the calculation about pH、pM、pX of the solution，the exact equation and simplified condition of pH calculation; distribution coefficient and distribution curve；the relationship of side reaction and conditional stability constant in complex titration, the relationship between the stability constant and conditional stability constant，the concept of minimum pH in complex titration and calculation methods；oxidation-reduction reaction and conditional electrode potential.
3.4 Complexation Equilibrium and Conditional Formation Constant
3.5 Oxidation- Reduction Equilibrium and Conditional Potential
3.6 Solubility Equilibria
3.7 Acid Base Titration Curve
3.8 Oxidation-Reduction Titration Curve
3.9 Complexometric Titration and Precipitation Titration Curve
Titrimetric analysis (Section 3.10~3.13)
课时目标：1．To emphasize on the grasping of calculation method on titration curve, the determination and calculation of titration end point and break range, the factors influencing titration break range；the principle that different indicators’ color change and selection methods, titration error and the conditions of direct titration.
3.10 Acid base indicators
3.11 Metal Ion Indicators
3.12 Redox Indicators
3.13 End Point Error and its Application
Titrimetric analysis (Section 3.14~3.17)
课时目标：To master the typical application and calculation of different titration methods.
3.14 Practical Application of Acid-Base Titration
3.15 Practical Application of Complexation Titration
3.16 Practical Application of Oxidation-Reduction Titration
3.17 Practical Application of Rrecipitation Titration
Electrochemical Analysis (Section 4.1~4.4)
课时目标：1．To be familiar with the classification of electrodes, to master the principle, structure and property of reference electrodes; the principle and structure of membrane electrode; the developing mechanism of the membrane potential of noncrystal membrane electrode (glass electrode) and crystal membrane electrode (fluoride electrode), the factors that influence the magnitude of membrane potential, developing reason of nonsymmetrical potential. To know the fundamentals of ion-selective electrodes, to master the significance, function and calculation equation of selectivity coefficient of the ion-selective electrodes, to be able to calculate the error caused by interfering ion according to selectivity coefficient.
4.1 Overview of Electrochemical Analysis
4.2 Principle of Potentiometry and Electrode Systems
4.3 Reference Electrodes
4.4 Ion Selective Electrodes
Electrochemical Analysis (Section 4.5~4.6)
课时目标：To grasp the measuring principle and calculation methods of solution pH, the function of the total ion strength adjustment buffer solution, standard addition method and its relevant calculation, the determining method on potential titration end point and its calculation.
4.5 Characteristics of Ion Selective Electrode
4.6 Application of Potential Analysis Method
Chromatography (Section 5.1~5.2)
课时目标：To know the characteristic, classification and application of chromatography well; to understand the separation process of chromatography; to master the definition of distribution coefficient, the relationship of distribution coefficient and the separation of components.To master plate theory, velocity theory, resolution, evaluation method of column efficiency, the factors that influence the column efficiency, the way to improve the column efficiency. To grasp the selection rule for operation conditions, the fundamental selection principle of stationary liquid, the effect of operation condition on analytical separation.
5.1 Overview of Chromatography
5.2 Theoretical Basis of Chromatography
Chromatography (Section 5.3~5.6)
课时目标：To know the chromatograph well, to master the fundamental components, structure process and key parts of gas chromatograph; to master the composition of the stationary phase, the classification method and the polar magnitude of stationary liquid；to grasp the structure , principle and property of thermal conductivity detector, to know the structure, principle and characteristics of hydrogen flame ionization detector well, to know the structure, principle and property of other detectors.To master qualitative and quantitative methods；the advantages and disadvantages and limitation of different quantitative methods.
5.3 Gas Chromatography
5.4 Capillary Gas Chromatography
5.5 High Performance Liquid Chromatography
5.6 Qualitative and Quantitative Analysis Methods
Ultraviolet Visible Spectroscopy (Section 6.1~6.3)
课时目标：1．To master the characteristics, fundamental principle, determining method and computing method of spectrophotometry. To master: the molecular absorption spectrum and the electron transition type，the selective absorption of matter for light, absorption rule of light，absorption curve, molar absorptivity and absorptivity coefficient, absorbance and transmittance, the reasons for discrepancy of Lambert-Beer law.
6.1 An introduction to Analytical Spectrometry
6.2 The Absorption of Electromagnetic Radiation and the Intensity of Spectral Line
6.3 Lambert Beer law
Ultraviolet Visible Spectroscopy (Section 6.4~6.6)
课时目标：1．To grasp the fundamental principle, main components and their function, main types and characteristics of spectrophotometer. To master color-developing reaction and the selection of the conditions and photometric measuring conditions, to know how to improve the sensitivity and selectivity of the measurement. 2．To master the principle and characteristic of differential spectrophotometry, to know about other photometric quantitative determining methods. 3．To know about the application of ultraviolet-visible spectrometry on the structure analysis of organic compounds and on other fields.
6.4 Instruments for UV-Vis Spectroscopy
6.5 Colorimetric Analysis
6.6 Quantitative Analysis Method
Atomic Absorption Spectroscopy
课时目标：1．To grasp the fundamentals and characteristics of atomic absorption spectrum, the characteristic resonance line of element, the parameters that described the absorption peak shape, the factors for the broadening of the absorption peak, peak absorptivity and absorptivity. To know the relationship between the number of atoms in ground state and the atomization temperature, the basis for quantitative analysis and the common methods for quantitative analysis. 2．To master the main components and the function of the atomic absorption spectrometer, to know the structure, procedures and types of the instrument. 3．To grasp the selection basis of analytical conditions, application fields and quantitative analytical methods; to know about the types of interference and restraining methods.
7.1 Overview of Atomic Absorption Spectroscopy
7.2 Principles of Atomic Absorption Spectroscopy
7.3 Instruments for Atomic Absorption Spectroscopy
7.4 Analyte Measurement
7.5 Quantitative Aanalysis Method
Infrared Spectroscopy
课时目标：1．To master the producing condition of infrared spectrum, primary vibration types of the groups in molecular, factors that influence the peak position, the relationship between infrared spectrum and molecular structure, method for analyzing infrared spectrum, the calculation of unsaturated degree, to be able to define the characteristic functional group of common organic compounds according to the infrared spectrum.
8.1 Overview of Infrared Spectroscopy
8.2 Basic Principle of Infrared Spectroscopy
8.3 Instruments for Infrared Spectroscopy and Sample Preparation
8.4 Characteristics of Infrared Spectrum
Nuclear Magnetic Resonance Spectroscopy
课时目标：To grasp the conditions producing magnetic nuclear resonance(NMR), NMR spectrum and chemical shift( H spectrum); to know the factors that influence chemical shift, spin coupling and spin splitting, information analysis of compound structure in NMR spectrum, to define the structure of simple organic compounds according to the NMR spectrum.
8.5 Basic Principle of NMR Spectroscopy
8.6 Relaxation and Instrument for NMR spectroscopy
8.7 Chemical Shift
8.8 Spin Spin Coupling
8.9 Qualitative Analysis – The Identification of Structural Feature
Mass Spectroscopy
课时目标：To master the fundamental principle of mass spectrometry(MS), general rule for cleavage of chemicals, the characteristic and judgment of molecular ion peak, general analytical method for MS.
8.10 Basic Principles and Instruments for Mass Spectroscopy
8.11 Characteristics and Interpretation of Molecular Mass Spectra
8.12 Cracking Types of Organic Molecules
8.13 Typical Mass Spectra of Organic Compounds
8.14 Spectrometric Identification of Organic Compounds
展开全部
预备知识
Dear students, in order to learn the course better, you need to have the following basic knowledge:
(1) The basic knowledge of differential and integral calculus;
(2) Chemical Equilibrium;
(3) Atomic and Molecular Orbital Theory;
(4) The basic concepts of chemical bond, polarity, electronegativity, and so on;
(5) The interaction between different molecules;
(6) The basic laws of light, electricity and magnetism.
You need to finish the courses of Advanced Mathematics, Physics, Inorganic Chemistry, General Chemistry, and Organic Chemistry.
参考资料
Textbook:
1.Analytical Chemistry(分析化学双语版第二版 ), edited by Ding Baojun（丁保君）,2017,7，Dalian University of Technology Press, ISBN:978-7-5685-0392-1
Reference Books:
1. Fundamentals of analytical chemistry, 9th Edition, by Douglas a. Skoog et al., Thomson Brooks / Cools Press.
2. Principles and Practice of Analytical Chemistry,5th Edition, by F. W. Fifield and D. Kealey, Blackwell Science Ltd.
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