The "Human Embryology" is a science that studies the normal human development as well as birth defects in the maternal uterus.
Bridges the gap between prenatal development and obstetrics, perinatal medicine, pediatrics and clinical anatomy
Develops knowledge concerning the beginning of life and the changes occurring during prenatal development
Builds an understanding of the causes of variations in human structure
Illuminates clinically oriented anatomy and explains how normal and abnormal relations develop
Supports the research and application of stem cells for treatment of certain chronic diseases
Our better understanding of “Human Embryology” will result in new techniques for prenatal diagnosis and treatment, therapeutic procedures to circumvent problems with infertility, mechanisms to prevent birth defects and the leading cause of infant mortality.
“Human Embryology” helps students understand
(1) how the gross and tissue-level morphologies that they have studied earlier are established during the development;
(2) what cellular behaviors normally contribute to such morphogenetic events;
(3) what molecular pathways work in the tissue-forming embryonic cells and how these pathways can participate in normal and pathological cellular behaviors of the adult cells;
(4) how developmental biological knowledge has been accumulated through utilizing a variety of non-human animal models;
(5) how pregnancy is diagnosed and monitored and what ethical issues we should bear in mind;
(6) how the understanding of embryological or developmental biological studies can contribute to regenerative medicine including clinical applications using embryonic stem cells and induced pluripotent stem cells.
Week 1 Introduction of Human Embryology
1.1 What is human embryology?
1.2 Brief history of embryology
1.3 Advances of modern embryology
1.4 What is teratology?
1.5 Papers about advances in embryology
1.6 From Minamata Disease to environmental health studies
Week 2 Gametogenesis and fertilization
2.1 Spermatogenesis
2.2 Oogensis
2.3 Fertilization
Test of week 2
Week 3 First week and second week of development: Cleavage to implantation
3.1 Clevage
3.2 Implantation
3.3 Papers about embryonic stem cell
Test for week 3
Week 4 Third to eight week of development: Gastrulation and differentiation of trilaminar disc
4.1 Gastrulation
4.2 Derivatives of ectoderm
4.3 Derivatives of mesoderm
4.4 Derivatives of endoderm
Test for week 4
Week 5 Fetal membrane and placenta
5.1 Fetal membrane-Amnion
5.2 Fetal membrane-Yolk sac and allantois
5.3 Fetal membrane-Chorion
5.4 Fetal membrane-Umbilical cord
5.5 Placenta
Test for week 5
Week 6 Development of the head and neck
6.1 Development of branchial arch and pharyngeal pouch
6.2 Development of face and malformations
6.3 Development of palate and cleft palate
6.4 Lessons for drug safety and regulation: Thalidomide tragedy
Test for week 6
Week 7 Development of the digestive and respiratory system
7.1 Development of primitive gut
7.2 Derivatives of forgut and clinical correlations
7.3 Derivatives of midgut and clinical correlations
7.4 Derivative of hindgut and clinical correlations
7.5 Development of respiratory system and clinical correlations
Test for week 7
Week 8 Development of urogenital system
8.1 Primordium of urogenital system
8.2 Development of kidney and ureter and clinical correlations
8.3 Development of bladder and clinical correlations
8.4 Development of gonad and clinical correlations
8.5 Development of genital duct and clinical correlations
8.6 Germline stem cell
Test for week 8
Week 9 Development of cardiovascular system
9.1 Formation of heart tube
9.2 Partitioning of atrial septum and clinical correlations
9.3 Partitioning of ventrical septum and clinical correlations
9.4 Partitioning of truncus arteriosus and bulbus cordis and clinical correlations
9.5 Fetal circulation and circulatory changes at birth
9.6 Paper about advances in intrauterine intervention therapy
Test for week 9
Appendix: The baby with three parents
The baby with three parents
After learning about Gross Anatomy, Histology, medical students or any students who are interested in reproductive mecidine and human development take this "Human Embryology”course to study how human organs are formed and what malformations may occur in each organ during development.
T. W. Sadler: Langman's Medical EmbryologyNinth Edition (Japanese, M. Yasuda Ed.), Medical Science International.
W. J. Larsen: Human Embryology 3rd Edition, Churchill Livingstone.
K. L. Moore and T. V. N. Persaud:The Developing Human 6th Edition (Japanese, H. Seguchi Ed.), W. B. Saunders.
Embryology (Board review series, sixth edition), Wolters Kluwer
Netter's atlas of human embryology, Larry R. Cochard, Saunders Elsevier
https://www.osmosis.org/
组织学与胚胎学(八年制教材,第一版,郭雨霁参编),人民卫生出版社,2005
奈特氏人体胚胎学彩色图谱(郭雨霁参译),人民卫生出版社,2004
组织学与胚胎学(英文版,郭雨霁参编),科学出版社,2014
Statement:
1. The pictures of this course mainly come from 《Langman's Medical Embryology》 、《Human Embryology》、《The Developing Human》、《组织学与胚胎学(八年制教材,第一版)》、《奈特氏人体胚胎学彩色图谱》、《组织学与胚胎学(英文版)》、《Netter's atlas of human embryology》. Some pictures and animations are from the internet (Baidu, Osmosis...), which are only used for reference in teaching, and thanks to the original author. If copyright is involved, please let me know.
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