Basic biochemistry is a compulsory course for undergraduates majoring in biology, agriculture, forestry, plant protection, horticulture, wine, etc., as well as a core course. This course is consisted of 78 sections, the basic chemical composition of living organisms, the chemical structure, spatial structure and basic biological functions of biological macromolecules are systematically and comprehensively are taught; Major metabolic process metabolic rule and metabolic regulation characteristics of sugar lipid protein and nucleic acid occurring in the animal plant microorganisms and human body. To help students fully understand the chemical essence and basic law characteristics of life activities and lay a good foundation for students to learn professional courses and solve related professional problems in the later period. 

   Chapter 1-5 is static biochemistry part, mainly introduces the basic components of life macromolecules characteristics and biological functions. Nucleic acid protein enzyme is one of the key contents of this part. Chapter 6-16 is the metabolism of substances in the body, also known as dynamic biochemistry part. Chapter 7 begins with the simplest and most common form of sugar metabolism, to learn about the decomposition of sugar and the anabolism of sugar in turn study the decomposition    and synthesis of fat, amino acids and nucleotides, and the biosynthesis of proteins and nucleic acids.

   Chapter 8 is about biological oxidation and oxidative phosphorylation, which is also one of the core contents of metabolism. It focuses on the synthesis process of how hydrogen was taken off from metabolites can be passed to oxygen to produce water and ATP coupling. The metabolism of four kinds of organic substances in the organism is interrelated and regulated in order. Metabolism is an essential feature of life. The decomposition and synthesis of sugar fat and the biosynthesis of nucleic acid and protein are the main contents of this course. In the last chapter, cell metabolism network and gene expression regulation are mainly taught about the four levels of metabolic regulation in different organisms and the regulation of gene expression in prokaryote and eukaryote. Through the above study, students can have a deeper understanding of the chemical nature of life process and lay a solid theoretical foundation for future professional courses.

Through teaching, this course aims to achieve the following teaching goals.

—— To help students understand and master the basic concepts and theories related to biochemistry；

——To help students understand the principles and methods of classical experiments in biochemistry；

—— To train students to correctly understand the chemical essence and laws of complex life phenomena and lay a good foundation for the cultivation of innovative thinking ability and comprehensive quality.

   Prerequisites are recommended:

Inorganic Chemistry, Organic Chemistry, General Biology, Botany, Zoology.

References:

1.  Guo Aiguang, Fan Sanhong, et al., basic biochemistry, 3rd edition, northwest A&F University, Higher Education Press, Published in August 2018, teaching materials for the 13th Five-year Plan of Agriculture and Forestry in national colleges and universities.

2. Zhu Shengen Xu Changfa, et al.,  《Textbook of Biochemistry》（forth Edition)，Higher Education Press, Jun 2017.

3. David L. Nelson, Michael M. Cox，Lehninger Principles of Biochemistry （Seventh Edition）, Jan, 2017. W. H. Freeman and Company New York.

1. TRENDS IN BIOCHEMICAL SCIENCES 

   https://www.cell.com/trends/biochemical-sciences/home

2.  Journal of Biological Chemistry

   http://www.jbc.org/